CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.20 | Single Sheet |
|
2.20.25 | N-terminal domain of TfIIb |
|
2.20.25.10 |
Domain Context
CATH Clusters
| Superfamily | 2.20.25.10 |
| Functional Family | DNA topoisomerase 1 |
Enzyme Information
| 5.99.1.2 |
DNA topoisomerase.
based on mapping to UniProt P06612
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.
-!- Brings about the conversion of one topological isomer of DNA into another, e.g. the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences (cf. EC 5.99.1.3).
|
UniProtKB Entries (1)
| P06612 |
TOP1_ECOLI
Escherichia coli K-12
DNA topoisomerase 1
|
PDB Structure
| PDB | 1YUA |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Solution structure of the C-terminal single-stranded DNA-binding domain of Escherichia coli topoisomerase I.
Biochemistry
|