CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.65 | Bacterial Topoisomerase I; domain 1 | |
3.30.65.10 | Bacterial Topoisomerase I, domain 1 |
Domain Context
CATH Clusters
Superfamily | Bacterial Topoisomerase I, domain 1 |
Functional Family | DNA topoisomerase 1 |
Enzyme Information
5.99.1.2 |
DNA topoisomerase.
based on mapping to UniProt P06612
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.
-!- Brings about the conversion of one topological isomer of DNA into another, e.g. the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences (cf. EC 5.99.1.3).
|
UniProtKB Entries (1)
P06612 |
TOP1_ECOLI
Escherichia coli K-12
DNA topoisomerase 1
|
PDB Structure
PDB | 1YUA |
External Links | |
Method | SOLUTION NMR |
Organism | Escherichia |
Primary Citation |
Solution structure of the C-terminal single-stranded DNA-binding domain of Escherichia coli topoisomerase I.
Biochemistry
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