CATH Classification

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family Polypeptide N-acetylgalactosaminyltransferase 1

Enzyme Information

2.4.1.41
Polypeptide N-acetylgalactosaminyltransferase.
based on mapping to UniProt O08912
UDP-N-acetyl-alpha-D-galactosamine + polypeptide = UDP + N-acetyl-alpha- D-galactosaminyl-polypeptide.
-!- The glycosyl residue is transferred to threonine or serine hydroxy groups on the polypeptide core of submaxillary mucin, kappa-casein, apofetuin and some other acceptors of high molecular mass.

UniProtKB Entries (1)

O08912
GALT1_MOUSE
Mus musculus
Polypeptide N-acetylgalactosaminyltransferase 1

PDB Structure

PDB 1XHB
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
The beginnings of mucin biosynthesis: The crystal structure of UDP-GalNAc:polypeptide {alpha}-N-acetylgalactosaminyltransferase-T1
Fritz, T.A., Hurley, J.H., Trinh, L.B., Shiloach, J., Tabak, L.A.
Proc.Natl.Acad.Sci.USA