CATH Classification

Domain Context

CATH Clusters

Superfamily Creatinase/prolidase N-terminal domain
Functional Family Xaa-Pro dipeptidase

Enzyme Information

3.4.13.9
Xaa-Pro dipeptidase.
based on mapping to UniProt O58885
Hydrolysis of Xaa-|-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro.
-!- Possibly thiol dependent. -!- Cytosolic from most animal tissues. -!- Belongs to peptidase family M24A. -!- Formerly EC 3.4.3.7.

UniProtKB Entries (1)

O58885
PEPQ_PYRHO
Pyrococcus horikoshii OT3
Xaa-Pro dipeptidase

PDB Structure

PDB 1WY2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of the Prolidase from Pyrococcus horikoshii OT3
Mizutani, H., Kunishima, N.
To be Published