CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Polymerase, chain B, domain 1
Functional Family DNA polymerase PolB subunit 1

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt D0VWU9
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

D0VWU9
D0VWU9_THEKO
Thermococcus kodakarensis KOD1
DNA polymerase

PDB Structure

PDB 1WN7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Mechanism for Coordination of Proofreading and Polymerase Activities in Archaeal DNA Polymerases
Kuroita, T., Matsumura, H., Yokota, N., Kitabayashi, M., Hashimoto, H., Inoue, T., Imanaka, T., Kai, Y.
J.Mol.Biol.