CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.47 | Peroxisomal Thiolase; Chain A, domain 1 |
|
3.40.47.10 | Thiolase/Chalcone synthase |
Domain Context
CATH Clusters
| Superfamily | 3.40.47.10 |
| Functional Family | Acetyl-CoA acetyltransferase, cytosolic variant |
Enzyme Information
| 2.3.1.9 |
Acetyl-CoA C-acetyltransferase.
based on mapping to UniProt Q9BWD1
2 acetyl-CoA = CoA + acetoacetyl-CoA.
|
UniProtKB Entries (1)
| Q9BWD1 |
THIC_HUMAN
Homo sapiens
Acetyl-CoA acetyltransferase, cytosolic
|
PDB Structure
| PDB | 1WL4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
High Resolution Crystal Structures of Human Cytosolic Thiolase (CT): A Comparison of the Active Sites of Human CT, Bacterial Thiolase, and Bacterial KAS I
J.Mol.Biol.
|