CATH Classification

Domain Context

CATH Clusters

Superfamily Glucose-6-phosphate isomerase like protein; domain 1
Functional Family Bifunctional phosphoglucose/phosphomannose isomerase

Enzyme Information

5.3.1.8
Mannose-6-phosphate isomerase.
based on mapping to UniProt Q8ZWV0
D-mannose 6-phosphate = D-fructose 6-phosphate.
5.3.1.9
Glucose-6-phosphate isomerase.
based on mapping to UniProt Q8ZWV0
D-glucose 6-phosphate = D-fructose 6-phosphate.
-!- Also catalyzes the anomerization of D-glucose 6-phosphate.

UniProtKB Entries (1)

Q8ZWV0
PGMI_PYRAE
Pyrobaculum aerophilum str. IM2
Bifunctional phosphoglucose/phosphomannose isomerase

PDB Structure

PDB 1TZB
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A novel phosphoglucose/phosphomannose isomease from the crenarchaeon Pyrobaculum aerophilum is a member of the PGI superfamily: structural evidence at 1.16 A resolution
Swan, M.K., Hansen, T., Schoenheit, P., Davies, C.
J.Biol.Chem.