CATH Classification

Domain Context

CATH Clusters

Superfamily Fumarylacetoacetase-like, C-terminal domain
Functional Family 2-Hydroxypent-2,4-dienoate hydratase LapE

Enzyme Information

4.2.1.80
2-oxopent-4-enoate hydratase.
based on mapping to UniProt P77608
4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H(2)O.
-!- Also acts, more slowly, on cis-2-oxohex-4-enoate, but not on the trans-isomer.

UniProtKB Entries (1)

P77608
MHPD_ECOLI
Escherichia coli K-12
2-keto-4-pentenoate hydratase

PDB Structure

PDB 1SV6
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of 2-hydroxypentadienoic acid hydratase from Escherichia Coli
Fedorov, A.A., Fedorov, E.V., Sharp, A., Almo, S.C.
To be Published