CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family Alkylmercury lyase

Enzyme Information

4.99.1.2
Alkylmercury lyase.
based on mapping to UniProt P77072
An alkylmercury + H(+) = an alkane + Hg(2+).
-!- Acts on CH(3)Hg(+) and a number of other alkylmercury compounds, in the presence of cysteine or other thiols, liberating mercury as a mercaptide.

UniProtKB Entries (1)

P77072
MERB_ECOLX
Escherichia coli
Alkylmercury lyase

PDB Structure

PDB 1S6L
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system.
Di Lello, P., Benison, G.C., Valafar, H., Pitts, K.E., Summers, A.O., Legault, P., Omichinski, J.G.
Biochemistry