CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase

Enzyme Information

1.1.1.10
L-xylulose reductase.
based on mapping to UniProt Q7Z4W1
Xylitol + NADP(+) = L-xylulose + NADPH.

UniProtKB Entries (1)

Q7Z4W1
DCXR_HUMAN
Homo sapiens
L-xylulose reductase

PDB Structure

PDB 1PR9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human L-xylulose reductase holoenzyme: probing the role of Asn107 with site-directed mutagenesis
El-Kabbani, O., Ishikura, S., Darmanin, C., Carbone, V., Chung, R.P.-T., Usami, N., Hara, A.
Proteins