CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.180 | Quinone Oxidoreductase; Chain A, domain 1 | |
3.90.180.10 | Medium-chain alcohol dehydrogenases, catalytic domain |
Domain Context
CATH Clusters
Superfamily | Medium-chain alcohol dehydrogenases, catalytic domain |
Functional Family | Putative zinc-binding alcohol dehydrogenase |
Enzyme Information
1.1.1.14 |
L-iditol 2-dehydrogenase.
based on mapping to UniProt Q00796
L-iditol + NAD(+) = L-sorbose + NADH.
-!- This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals. -!- It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol. -!- Enzymes from different organisms or tissues display different substrate specificity. -!- The enzyme is specific to NAD(+) and can not use NADP(+).
|
UniProtKB Entries (1)
Q00796 |
DHSO_HUMAN
Homo sapiens
Sorbitol dehydrogenase
|
PDB Structure
PDB | 1PL6 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.
Structure
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