CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1090 | Dehydroquinate synthase-like, alpha domain |
|
1.20.1090.10 | Dehydroquinate synthase-like - alpha domain |
Domain Context
CATH Clusters
| Superfamily | Dehydroquinate synthase-like - alpha domain |
| Functional Family | Putative alcohol dehydrogenase 3 |
Enzyme Information
| 1.1.1.1 |
Alcohol dehydrogenase.
based on mapping to UniProt Q46856
(1) An alcohol + NAD(+) = an aldehyde or ketone + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
-!- Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. -!- The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
|
| 1.1.1.- |
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q46856
|
| 1.1.1.2 |
Alcohol dehydrogenase (NADP(+)).
based on mapping to UniProt Q46856
An alcohol + NADP(+) = an aldehyde + NADPH.
-!- Some members of this group oxidize only primary alcohols; others act also on secondary alcohols. -!- May be identical with EC 1.1.1.19, EC 1.1.1.33 and EC 1.1.1.55. -!- Re-specific with respect to NADPH.
|
UniProtKB Entries (1)
| Q46856 |
YQHD_ECOLI
Escherichia coli K-12
Alcohol dehydrogenase YqhD
|
PDB Structure
| PDB | 1OJ7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of E.Coli Alcohol Dehydrogenase Yqhd: Evidence of a Covalently Modified Nadp Coenzyme
J.Mol.Biol.
|
