CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1280.10
Functional Family Ribosomal RNA large subunit methyltransferase H

Enzyme Information

2.1.1.177
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase.
based on mapping to UniProt Q9WZU8
S-adenosyl-L-methionine + pseudouridine(1915) in 23S rRNA = S-adenosyl-L- homocysteine + N(3)-methylpseudouridine(1915) in 23S rRNA.
-!- YbeA does not methylate uridine at position 1915.

UniProtKB Entries (1)

Q9WZU8
RLMH_THEMA
Thermotoga maritima MSB8
Ribosomal RNA large subunit methyltransferase H

PDB Structure

PDB 1O6D
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural analysis of a set of proteins resulting from a bacterial genomics project
Badger, J., Sauder, J.M., Adams, J.M., Antonysamy, S., Bain, K., Bergseid, M.G., Buchanan, S.G., Buchanan, M.D., Batiyenko, Y., Christopher, J.A., Emtage, S., Eroshkina, A., Feil, I., Furlong, E.B., Gajiwala, K.S., Gao, X., He, D., Hendle, J., Huber, A., Hoda, K., Kearins, P., Kissinger, C., Laubert, B., Lewis, H.A., Lin, J., Loomis, K., Lorimer, D., Louie, G., Maletic, M., Marsh, C.D., Miller, I., Molinari, J., Muller-Dieckmann, H.J., Newman, J.M., Noland, B.W., Pagarigan, B., Park, F., Peat, T.S., Post, K.W., Radojicic, S., Ramos, A., Romero, R., Rutter, M.E., Sanderson, W.E., Schwinn, K.D., Tresser, J., Winhoven, J., Wright, T.A., Wu, L., Xu, J., Harris, T.J.
Proteins