CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.180 | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 |
|
3.10.180.10 | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 |
| Functional Family | Glutathione transferase FosA |
Enzyme Information
| 2.5.1.18 |
Glutathione transferase.
based on mapping to UniProt Q56415
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
|
UniProtKB Entries (1)
| Q56415 |
FOSA_SERMA
Serratia marcescens
Glutathione transferase FosA
|
PDB Structure
| PDB | 1NPB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of fosfomycin resistance protein FosA from transposon Tn2921.
Protein Sci.
|