CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.230 | Ribosomal Protein S5; domain 2 |
|
3.30.230.10 |
Domain Context
CATH Clusters
| Superfamily | 3.30.230.10 |
| Functional Family | Dna topoisomerase 6 subunit b |
Enzyme Information
| 5.99.1.3 |
DNA topoisomerase (ATP-hydrolyzing).
based on mapping to UniProt O05207
ATP-dependent breakage, passage and rejoining of double-stranded DNA.
-!- Can introduce negative superhelical turns into double-stranded circular DNA. -!- One unit has nicking-closing activity, and another catalyzes super- twisting and hydrolysis of ATP (cf. EC 5.99.1.2).
|
UniProtKB Entries (1)
| O05207 |
TOP6B_SULSH
Sulfolobus shibatae
Type 2 DNA topoisomerase 6 subunit B
|
PDB Structure
| PDB | 1MU5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution
Embo J.
|
