CATH Classification

Domain Context

CATH Clusters

Superfamily 2.70.98.10
Functional Family Glucan 14-alpha-glucosidase Cga

Enzyme Information

3.2.1.3
Glucan 1,4-alpha-glucosidase.
based on mapping to UniProt O85672
Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose.
-!- Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides. -!- This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. -!- EC 3.2.1.20 from mammalian intestine can catalyze similar reactions.

UniProtKB Entries (1)

O85672
O85672_THETR
Thermoanaerobacterium thermosaccharolyticum
Glucoamylase

PDB Structure

PDB 1LF6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure and evolution of prokaryotic glucoamylase
Aleshin, A.E., Feng, P.-H., Honzatko, R.B., Reilly, P.J.
J.Mol.Biol.
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