CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Chymotrypsinogen B

Enzyme Information

3.4.21.1
Chymotrypsin.
based on mapping to UniProt P07338
Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.5 and EC 3.4.4.6.

UniProtKB Entries (1)

P07338
CTRB1_RAT
Rattus norvegicus
Chymotrypsinogen B

PDB Structure

PDB 1KDQ
External Links
Method X-RAY DIFFRACTION
Organism Saccharomyces
Primary Citation
Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-specific Stabilization of the Substrate-binding Site
Szabo, E., Venekei, I., Bocskei, Z., Naray-Szabo, G., Graf, L.
J.Mol.Biol.