CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family Putative P4-specific DNA primase

Enzyme Information

2.7.7.-
Nucleotidyltransferases.
based on mapping to UniProt P10277
3.6.4.12
DNA helicase.
based on mapping to UniProt P10277
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).

UniProtKB Entries (1)

P10277
PRIM_BPP4
Enterobacteria phage P4
Putative P4-specific DNA primase

PDB Structure

PDB 1KA8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Phage P4 origin-binding domain structure reveals a mechanism for regulation of DNA-binding activity by homo- and heterodimerization of winged helix proteins.
Yeo, H.J., Ziegelin, G., Korolev, S., Calendar, R., Lanka, E., Waksman, G.
Mol.Microbiol.