CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.140.60
Functional Family

Enzyme Information

4.6.1.1
Adenylate cyclase.
based on mapping to UniProt P40136
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.

UniProtKB Entries (1)

P40136
CYAA_BACAN
Bacillus anthracis
Calmodulin-sensitive adenylate cyclase

PDB Structure

PDB 1K90
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Drum, C.L., Yan, S.-Z., Bard, J., Shen, Y.-Q., Lu, D., Soelaiman, S., Grabarek, Z., Bohm, A., Tang, W.-J.
Nature