CATH Classification

Domain Context

CATH Clusters

Superfamily Protein-tyrosine phosphatase, YopH, N-terminal domain
Functional Family Tyrosine-protein phosphatase YopH

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P08538
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P08538
YOPH_YERPS
Yersinia pseudotuberculosis IP 32953
Tyrosine-protein phosphatase YopH

PDB Structure

PDB 1K46
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the type III secretion and substrate-binding domain of Yersinia YopH phosphatase.
Smith, C.L., Khandelwal, P., Keliikuli, K., Zuiderweg, E.R., Saper, M.A.
Mol.Microbiol.