CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1110 | Calcium-transporting ATPase, transmembrane domain |
|
1.20.1110.10 | Calcium-transporting ATPase, transmembrane domain |
Domain Context
CATH Clusters
| Superfamily | Calcium-transporting ATPase, transmembrane domain |
| Functional Family | Calcium-transporting ATPase, endoplasmic reticulum-type |
Enzyme Information
| 3.6.3.8 |
Calcium-transporting ATPase.
based on mapping to UniProt P04191
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in Saccharomyces cerevisiae. -!- The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions. -!- Formerly EC 3.6.1.38.
|
UniProtKB Entries (1)
| P04191 |
AT2A1_RABIT
Oryctolagus cuniculus
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
|
PDB Structure
| PDB | 1IWO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural changes in the calcium pump accompanying the dissociation of calcium
Nature
|
