CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.1180 | Golgi alpha-mannosidase II |
Domain Context
CATH Clusters
| Superfamily | Golgi alpha-mannosidase II |
| Functional Family | Alpha mannosidase II, isoform B |
Enzyme Information
| 3.2.1.114 |
Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase.
based on mapping to UniProt Q24451
Hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
-!- Involved in the synthesis of glycoproteins.
|
UniProtKB Entries (1)
| Q24451 |
MAN2_DROME
Drosophila melanogaster
Alpha-mannosidase 2
|
PDB Structure
| PDB | 1HWW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Drosophila |
| Primary Citation |
Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J.
|