CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Glyceraldehyde-3-phosphate dehydrogenase, type I

Enzyme Information

1.2.1.12
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt P17721
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.
1.2.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt P17721

UniProtKB Entries (1)

P17721
G3P_THEMA
Thermotoga maritima MSB8
Glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 1HDG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of holo-glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima at 2.5 A resolution.
Korndorfer, I., Steipe, B., Huber, R., Tomschy, A., Jaenicke, R.
J.Mol.Biol.