CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.130 | P-30 Protein |
|
3.10.130.10 | Ribonuclease A-like domain |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease A-like domain |
| Functional Family | Angiogenin ribonuclease 6 |
Enzyme Information
| 3.1.27.- |
Endoribonucleases producing other than 5'-phosphomonoesters.
based on mapping to UniProt P03950
|
| 3.1.27.5 |
Pancreatic ribonuclease.
based on mapping to UniProt P61823
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates.
-!- Similar enzymes: venom RNase, Thiobacillus thioparus RNase, Xenopus laevis RNase, Rhizopus oligosporus RNase, ribonuclease M. -!- Formerly EC 2.7.7.16 and EC 3.1.4.22.
|
UniProtKB Entries (2)
| P61823 |
RNAS1_BOVIN
Bos taurus
Ribonuclease pancreatic
|
| P03950 |
ANGI_HUMAN
Homo sapiens
Angiogenin
|
PDB Structure
| PDB | 1GV7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Guest-Host Crosstalk in an Angiogenin-RNase A Chimeric Protein
Biochemistry
|