CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.130 | P-30 Protein |
|
3.10.130.10 | Ribonuclease A-like domain |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease A-like domain |
| Functional Family | Eosinophil cationic-type ribonuclease 3 |
Enzyme Information
| 3.1.27.5 |
Pancreatic ribonuclease.
based on mapping to UniProt P10153
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates.
-!- Similar enzymes: venom RNase, Thiobacillus thioparus RNase, Xenopus laevis RNase, Rhizopus oligosporus RNase, ribonuclease M. -!- Formerly EC 2.7.7.16 and EC 3.1.4.22.
|
UniProtKB Entries (1)
| P10153 |
RNAS2_HUMAN
Homo sapiens
Non-secretory ribonuclease
|
PDB Structure
| PDB | 1GQV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Atomic Resolution (0.98 A) Structure of Eosinophil-Derived Neurotoxin
Biochemistry
|