CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.10 | S15/NS1, RNA-binding |
Domain Context
CATH Clusters
| Superfamily | S15/NS1, RNA-binding |
| Functional Family | Bifunctional aminoacyl-tRNA synthetase isoform 1 |
Enzyme Information
| 6.1.1.17 |
Glutamate--tRNA ligase.
based on mapping to UniProt P07814
ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).
|
| 6.1.1.15 |
Proline--tRNA ligase.
based on mapping to UniProt P07814
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
|
UniProtKB Entries (1)
| P07814 |
SYEP_HUMAN
Homo sapiens
Bifunctional glutamate/proline--tRNA ligase
|
PDB Structure
| PDB | 1FYJ |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Structural analysis of multifunctional peptide motifs in human bifunctional tRNA synthetase: identification of RNA-binding residues and functional implications for tandem repeats.
Biochemistry
|