CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleotide cyclase
Functional Family Receptor-type adenylate cyclase A

Enzyme Information

4.6.1.1
Adenylate cyclase.
based on mapping to UniProt Q99279
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.

UniProtKB Entries (1)

Q99279
CY41_TRYBB
Trypanosoma brucei brucei
Receptor-type adenylate cyclase GRESAG 4.1

PDB Structure

PDB 1FX2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state.
Bieger, B., Essen, L.O.
EMBO J.