CATH Classification

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family Probable udp-n-acetylglucosamine 2-epimerase protein

Enzyme Information

5.1.3.14
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing).
based on mapping to UniProt P27828
UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-mannosamine.
-!- This bacterial enzyme catalyzes the reversible interconversion of UDP-GlcNAc and UDP-ManNAc. -!- The latter is used in a variety of bacterial polysaccharide biosyntheses. -!- Cf. EC 3.2.1.183.

UniProtKB Entries (1)

P27828
WECB_ECOLI
Escherichia coli K-12
UDP-N-acetylglucosamine 2-epimerase

PDB Structure

PDB 1F6D
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases.
Campbell, R.E., Mosimann, S.C., Tanner, M.E., Strynadka, N.C.
Biochemistry