CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Nicotinamide-nucleotide adenylyltransferase

Enzyme Information

2.7.7.1
Nicotinamide-nucleotide adenylyltransferase.
based on mapping to UniProt O26253
ATP + nicotinamide ribonucleotide = diphosphate + NAD(+).
-!- Nicotinate nucleotide can also act as acceptor. -!- See also EC 2.7.7.18.

UniProtKB Entries (1)

O26253
NADM_METTH
Methanothermobacter thermautotrophicus str. Delta H
Nicotinamide-nucleotide adenylyltransferase

PDB Structure

PDB 1EJ2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.
Saridakis, V., Christendat, D., Kimber, M.S., Dharamsi, A., Edwards, A.M., Pai, E.F.
J.Biol.Chem.