CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.10 | Roll | |
3.10.130 | P-30 Protein | |
3.10.130.10 | Ribonuclease A-like domain |
Domain Context
CATH Clusters
Superfamily | Ribonuclease A-like domain |
Functional Family | Ribonuclease pancreatic beta-type |
Enzyme Information
3.1.27.5 |
Pancreatic ribonuclease.
based on mapping to UniProt P07998
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates.
-!- Similar enzymes: venom RNase, Thiobacillus thioparus RNase, Xenopus laevis RNase, Rhizopus oligosporus RNase, ribonuclease M. -!- Formerly EC 2.7.7.16 and EC 3.1.4.22.
|
UniProtKB Entries (1)
P07998 |
RNAS1_HUMAN
Homo sapiens
Ribonuclease pancreatic
|
PDB Structure
PDB | 1DZA |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Three-Dimensional Structure of a Human Pancreatic Ribonuclease Variant, a Step Forward in the Design of Cytotoxic Ribonucleases
J.Mol.Biol.
|