CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Fermentative D-lactate dehydrogenase, NAD-dependent |
Enzyme Information
| 1.1.1.- |
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt P17584
|
| 1.1.1.28 |
D-lactate dehydrogenase.
based on mapping to UniProt P17584
(R)-lactate + NAD(+) = pyruvate + NADH.
|
UniProtKB Entries (1)
| P17584 |
DHD2_LACPA
Lactobacillus paracasei
D-2-hydroxyisocaproate dehydrogenase
|
PDB Structure
| PDB | 1DXY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution.
J.Mol.Biol.
|
