CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Fermentative D-lactate dehydrogenase, NAD-dependent

Enzyme Information

1.1.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt P17584
1.1.1.28
D-lactate dehydrogenase.
based on mapping to UniProt P17584
(R)-lactate + NAD(+) = pyruvate + NADH.

UniProtKB Entries (1)

P17584
DHD2_LACPA
Lactobacillus paracasei
D-2-hydroxyisocaproate dehydrogenase

PDB Structure

PDB 1DXY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution.
Dengler, U., Niefind, K., Kiess, M., Schomburg, D.
J.Mol.Biol.