CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1220 | TPP-binding domain |
Domain Context
CATH Clusters
| Superfamily | TPP-binding domain |
| Functional Family | NAD(P) transhydrogenase subunit beta |
Enzyme Information
| 1.6.1.2 |
NAD(P)(+) transhydrogenase (Re/Si-specific).
based on mapping to UniProt Q13423
NADPH + NAD(+) = NADP(+) + NADH.
-!- The enzyme from heart mitochondria is Re-specific with respect to NAD(+) and Si-specific with respect to NADP(+) (cf. EC 1.6.1.1.).
|
UniProtKB Entries (1)
| Q13423 |
NNTM_HUMAN
Homo sapiens
NAD(P) transhydrogenase, mitochondrial
|
PDB Structure
| PDB | 1DJL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The high-resolution structure of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase from human heart mitochondria.
Structure Fold.Des.
|