CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.465 | Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 |
|
3.30.465.10 |
Domain Context
CATH Clusters
| Superfamily | 3.30.465.10 |
| Functional Family | P-cresol methylhydroxylase flavoprotein subunit |
Enzyme Information
| 1.17.99.1 |
4-methylphenol dehydrogenase (hydroxylating).
based on mapping to UniProt P09788
4-methylphenol + 2 acceptor + H(2)O = 4-hydroxybenzaldehyde + 2 reduced acceptor.
-!- Phenazine methosulfate can act as acceptor. -!- A quinone methide is probably formed as intermediate. -!- The first hydroxylation forms 4-hydroxybenzyl alcohol; a second hydroxylation converts this into 4-hydroxybenzaldehyde.
|
UniProtKB Entries (1)
| P09788 |
DH4C_PSEPU
Pseudomonas putida
4-cresol dehydrogenase [hydroxylating] flavoprotein subunit
|
PDB Structure
| PDB | 1DII |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of the flavocytochrome p-cresol methylhydroxylase and its enzyme-substrate complex: gated substrate entry and proton relays support the proposed catalytic mechanism.
J.Mol.Biol.
|