CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.140
Functional Family DNA topoisomerase 3

Enzyme Information

5.99.1.2
DNA topoisomerase.
based on mapping to UniProt P14294
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.
-!- Brings about the conversion of one topological isomer of DNA into another, e.g. the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences (cf. EC 5.99.1.3).

UniProtKB Entries (1)

P14294
TOP3_ECOLI
Escherichia coli K-12
DNA topoisomerase 3

PDB Structure

PDB 1D6M
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of Escherichia coli DNA topoisomerase III.
Mondragon, A., DiGate, R.
Structure Fold.Des.