CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | DNA methylase family protein |
Enzyme Information
| 2.1.1.113 |
Site-specific DNA-methyltransferase (cytosine-N(4)-specific).
based on mapping to UniProt P11409
S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N(4)-methylcytosine.
-!- This is a large group of enzymes, the majority of which, with enzymes of similar site specificity listed as EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5, form so-called restriction-modification systems. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
| 2.1.1.- |
Methyltransferases.
based on mapping to UniProt P11409
|
UniProtKB Entries (1)
| P11409 |
MTP2_PROHU
Proteus hauseri
Modification methylase PvuII
|
PDB Structure
| PDB | 1BOO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of pvu II DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment.
Nucleic Acids Res.
|