CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.10 | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Domain Context
CATH Clusters
| Superfamily | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| Functional Family | Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor |
Enzyme Information
| 6.3.4.15 |
Biotin--[acetyl-CoA-carboxylase] ligase.
based on mapping to UniProt P06709
ATP + biotin + apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [acetyl-CoA:carbon-dioxide ligase (ADP-forming)].
|
UniProtKB Entries (1)
| P06709 |
BIRA_ECOLI
Escherichia coli K-12
Bifunctional ligase/repressor BirA
|
PDB Structure
| PDB | 1BIA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.
Proc.Natl.Acad.Sci.USA
|