CATH Classification

Domain Context

CATH Clusters

Superfamily Laminin
Functional Family Neurogenic locus notch protein 1

Enzyme Information

3.4.21.21
Coagulation factor VIIa.
based on mapping to UniProt P08709
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- Formed from the precursor factor VII. -!- The cattle enzyme is more readily inhibited by diisopropyl fluorophosphate than the human. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P08709
FA7_HUMAN
Homo sapiens
Coagulation factor VII

PDB Structure

PDB 1BF9
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the N-terminal EGF-like domain from human factor VII.
Muranyi, A., Finn, B.E., Gippert, G.P., Forsen, S., Stenflo, J., Drakenberg, T.
Biochemistry