CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein

Enzyme Information

1.4.1.2
Glutamate dehydrogenase.
based on mapping to UniProt P24295
L-glutamate + H(2)O + NAD(+) = 2-oxoglutarate + NH(3) + NADH.

UniProtKB Entries (1)

P24295
DHE2_CLOSY
[Clostridium] symbiosum
NAD-specific glutamate dehydrogenase

PDB Structure

PDB 1AUP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Determinants of substrate specificity in the superfamily of amino acid dehydrogenases.
Baker, P.J., Waugh, M.L., Wang, X.G., Stillman, T.J., Turnbull, A.P., Engel, P.C., Rice, D.W.
Biochemistry