CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate/ornithine carbamoyltransferase
Functional Family Ornithine carbamoyltransferase, catabolic

Enzyme Information

2.1.3.3
Ornithine carbamoyltransferase.
based on mapping to UniProt P04391
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
-!- The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.

UniProtKB Entries (1)

P04391
OTC1_ECOLI
Escherichia coli K-12
Ornithine carbamoyltransferase subunit I

PDB Structure

PDB 1AKM
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure at 2.8 A resolution of anabolic ornithine transcarbamylase from Escherichia coli.
Jin, L., Seaton, B.A., Head, J.F.
Nat.Struct.Biol.