CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Chemotaxis protein methyltransferase (CheR)

Enzyme Information

2.1.1.80
Protein-glutamate O-methyltransferase.
based on mapping to UniProt P07801
S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester.
-!- Forms ester groups with L-glutamate residues in a number of membrane proteins. -!- Formerly EC 2.1.1.24.

UniProtKB Entries (1)

P07801
CHER_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Chemotaxis protein methyltransferase

PDB Structure

PDB 1AF7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine.
Djordjevic, S., Stock, A.M.
Structure