CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Alcohol dehydrogenase 1

Enzyme Information

1.1.1.1
Alcohol dehydrogenase.
based on mapping to UniProt P10807
(1) An alcohol + NAD(+) = an aldehyde or ketone + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
-!- Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. -!- The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.

UniProtKB Entries (1)

P10807
ADH_DROLE
Scaptodrosophila lebanonensis
Alcohol dehydrogenase

PDB Structure

PDB 1A4U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution.
Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
J.Mol.Biol.