The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
152021
56984
3D
5i4cA00 - 86.3
151049
50039
EC
3D
1e2bA00 - 75.1
151774
49475
EC
3D
2iksA01 - 65.8
10147
49260
3D
2iksA02 - 43.5
37185
46258
EC
3D
1a04A01 - 15.0
151841
43269
EC
3D
1a0oA00 - 94.9
140616
40818
EC
- - 75.6
126788
40011
3D
3f6cA00 - 17.1
152103
38514
EC
3D
1gubA02 - 89.5
150967
37583
EC
- - 60.2
150857
36383
3D
2pkxA00 - 53.3
151181
36356
EC
3D
1ba2A01 - 75.0
151463
36309 - - 79.8
28828
36088 - - 62.8
151465
35711
EC
- - 74.9
93081
32698
3D
1glgA01 - 64.7
7225
32620 - - 36.1
65182
32226 - - 18.0
143443
31866
EC
- - 64.3
10578
31777 - - 26.4
131899
31694 - - 13.6
140615
30903
EC
3D
2kyrA00 - 50.8
151866
30864
EC
3D
4eukA00 - 93.9
152097
29909
EC
3D
1dcfA00 - 93.4
151905
27779
EC
3D
1d5wA00 - 95.0
100790
26613
3D
3eodA00 - 57.2
152005
23227
3D
1usgA02 - 95.0
59539
22586
EC
- - 27.8
150738
22149
3D
1usgA01 - 89.5
151899
20827
EC
3D
1vkrA00 - 92.4
141871
20342
EC
3D
4tn5A00 - 47.6
150848
20233
3D
2qv0A00 - 63.1
151766
18957
EC
3D
1bdhA03 - 91.4
151947
17729
EC
3D
1xwwA00 - 88.4
152057
14046
EC
3D
1f51E00 - 96.2
151482
13845
EC
- - 92.2
108957
13421
EC
3D
1abeA01 - 69.5
13377
13370
EC
3D
1abeA02 - 66.3
86039
13015 - - 11.2
143029
11951
EC
3D
1tvmA01 - 60.4
25460
11492 - - 24.3
150784
9956
EC
- - 54.1
151045
9888
EC
3D
3m9wA01 - 74.3
151864
9384
EC
3D
1m5tA00 - 98.0
151771
8291
EC
3D
2r4qA00 - 95.1
151438
6555
EC
3D
1a2oA01 - 94.8
151818
5794
EC
3D
1jl3A00 - 99.2
152135
5543
EC
3D
3lukA01 - 89.0
104797
5381
EC
- - 60.7
152268
5374
EC
3D
2fqwA02 - 94.6
100713
5208 - - 41.2
144263
5002
EC
- - 12.6
151577
4068
EC
3D
3t8yA00 - 98.4
140369
3848
EC
- - 63.4
60483
3803
EC
3D
2ayxA02 - 55.6
28643
3637 - - 16.8
151521
3526
EC
3D
4s04A01 - 95.6
35323
3483 - - 7.7
151671
3421
EC
- - 88.6
123982
3306
EC
- - 48.1
93659
3249 - - 0.0
151898
3140
EC
- - 91.4
150813
3113
3D
1tjyA02 - 71.8
150963
3079
3D
1tjyA01 - 60.4
108762
3073 - - 6.1
151695
CheY
2987
EC
3D
1tmyA00 - 94.3
23269
2903
EC
- - 10.5
58642
2795 - - 20.6
151653
2637
EC
- - 96.4
150770
2616 - - 67.9
16951
2498 - - 0.0
152233
2446 - - 82.4
151552
2413
EC
- - 93.2
151782
2331 - - 69.2
150988
2308
EC
- - 23.4
151867
2146
EC
- - 97.6
150919
1857 - - 23.2
150767
1845 - - 14.3
88661
1726 - - 39.7
151188
1686
EC
- - 66.2
152251
1662
EC
3D
3n0rA02 - 90.7
101109
1623 - - 38.5
151525
1512
EC
3D
2fepA01 - 80.7
12767
1296 - - 0.0
68070
1261 - - 53.3
150858
1259
EC
3D
3lucA01 - 85.3
151540
1198
3D
1dz3A00 - 93.6
151533
1147
EC
- - 93.1
141117
952
EC
- - 71.5
100684
947
EC
3D
1gubA01 - 33.2
152217
873
EC
- - 86.8
151896
838 - - 91.5
151167
824
EC
3D
2wjwA01 - 82.2
152259
707
EC
- - 95.3
45891
704
EC
- - 25.7
150824
691
EC
3D
4xaqA01 - 79.9
151424
578
3D
3ks9A01 - 86.8
67898
566
3D
2vk2A01 - 70.5
79539
549
EC
- - 11.6
143589
546 - - 28.5
150956
493 - - 85.3
63882
488 - - 4.3
151488
482
EC
- - 89.7
151763
447 - - 84.0
152104
400
EC
- - 97.0
49104
371
EC
- - 12.7
150789
341
EC
- - 37.0
151810
331
EC
- - 86.7
151162
321
EC
3D
3urmA01 - 87.0
151477
309
EC
- - 97.2
6367
307
3D
3ks9A02 - 85.5
152323
305 - - 70.9
151348
304
EC
- - 25.7
151064
297 - - 84.0
152291
273
EC
- - 96.7
121840
260 - - 42.9
33606
250
3D
1s8nA01 - 36.1
35087
245 - - 4.1
150991
225
3D
2wjwA02 - 61.5
150739
224
3D
3q41A02 - 85.6
150746
222
3D
4gpaA02 - 64.6
112088
219 - - 34.3
151172
213 - - 52.8
9568
206 - - 9.3
82317
203 - - 11.9
100715
198 - - 30.7
151522
198
EC
- - 94.8
2585
197 - - 1.2
43596
197 - - 0.0
80081
196 - - 0.0
152317
195
EC
- - 85.7
358
190
3D
3mq4A01 - 77.5
49654
189 - - 4.0
289
182 - - 39.8
150925
182 - - 24.1
134657
174
EC
- - 33.2
151478
168
EC
- - 94.2
100246
167
EC
- - 0.0
150836
165
3D
1jx6A01 - 67.7
28047
161
3D
3o21A02 - 60.9
150941
161 - - 82.1
3246
159
3D
3ip5A01 - 69.3
150881
158 - - 25.2
151799
156
EC
- - 74.2
138847
151
EC
- - 46.9
150909
150
3D
3sajA02 - 46.3
151186
150 - - 75.0
126828
148 - - 3.6
25230
148 - - 3.1
136858
144
3D
4pz0A01 - 20.8
152088
143 - - 88.0
27785
142 - - 11.3
152153
141
EC
- - 71.3
13866
139
EC
- - 49.5
151420
139 - - 56.1
54080
134 - - 55.1
46835
133
3D
4xfkA02 - 7.4
152075
130
EC
- - 94.3
1917
130 - - 0.0
152014
125 - - 81.7
19617
122 - - 11.8
76695
119 - - 59.6
38314
118 - - 65.6
87839
114
EC
- - 31.5
78982
114 - - 63.4
150792
112
3D
4mqeA01 - 75.9
150845
112 - - 75.6
103966
111 - - 59.6
151691
110
3D
5fbkA01 - 93.6
142966
108
EC
- - 39.0
151148
105 - - 67.5
151173
105 - - 56.5
140855
100 - - 13.9
750
100
3D
3mq4A02 - 67.5
150987
99
EC
- - 65.3
141131
96
EC
- - 9.4
29589
89 - - 9.9
151688
88
EC
- - 86.0
151541
88 - - 90.4
118954
87 - - 9.4
151063
87 - - 31.1
151050
86 - - 74.5
152325
84
EC
- - 85.0
150737
84 - - 26.5
150841
82
3D
5kc8A02 - 61.7
151332
79 - - 89.8
150893
77
3D
4f11A02 - 55.4
143043
74
EC
- - 18.2
152064
73
EC
- - 55.2
24156
72
EC
- - 27.0
10729
71 - - 50.5
17010
68 - - 2.6
150996
67
EC
- - 72.2
44735
65 - - 9.3
67558
64 - - 0.0
82466
64 - - 0.0
104568
64
3D
4ldzA01 - 12.4
151850
60 - - 82.2
138450
59
EC
- - 27.2
39651
56 - - 17.7
113763
54 - - 0.0
112065
54 - - 16.4
151692
54 - - 68.1
8927
54 - - 1.8
150749
54 - - 58.8
151984
54 - - 71.6
79133
53 - - 17.0
126808
53 - - 19.4
11466
52 - - 13.0
151151
52 - - 71.0
124870
52 - - 4.7
27769
51 - - 20.7
8862
50
3D
1jdnA02 - 46.2
151290
50
EC
- - 38.2
1420
50
3D
4f11A01 - 36.6
121770
50 - - 10.4
11075
50 - - 3.1
16959
49 - - 0.0
151506
49 - - 84.1
93033
49
EC
- - 7.3
151342
47
EC
- - 58.8
143032
47
EC
- - 8.3
126320
46 - - 23.0
150706
45
EC
3D
1dp4A01 - 34.6
151163
43
EC
- - 84.1
96817
42
EC
- - 2.3
151359
42 - - 59.0
94448
41 - - 0.0
141143
40
EC
- - 3.2
151753
40 - - 52.2
85318
40
EC
- - 3.1
143
40
3D
5fbhA01 - 63.6
151259
39 - - 43.8
152054
YbdK
39 - - 89.4
45052
38 - - 9.6
151154
38
EC
- - 62.9
108447
38 - - 12.0
115461
38 - - 10.0
12136
37 - - 0.0
75455
37 - - 0.0
126802
37 - - 2.0
138387
37
EC
- - 8.8
22711
37 - - 36.1
7783
37 - - 30.6
143866
37 - - 1.2
130387
36 - - 0.0
14829
36
EC
- - 24.7
121786
36 - - 0.0
151444
36 - - 78.0
9923
36 - - 0.0
11673
35 - - 13.1
111977
34 - - 7.6
150890
33 - - 27.4
33551
33
EC
- - 8.4
150908
32
3D
4qpjC00 - 40.5
152241
31 - - 94.5
140190
30
EC
- - 6.5
131791
29
EC
- - 9.1
152294
29
EC
- - 88.4
10947
29 - - 1.2
140628
29 - - 2.1
152252
29 - - 89.9
96753
28 - - 17.6
124711
27 - - 12.8
1916
27 - - 6.0
41270
27 - - 10.9
27996
27 - - 50.7
151185
27
EC
- - 77.9
7055
27
3D
5kc9A02 - 39.6
150910
26
EC
- - 0.9
150859
26 - - 49.5
18446
26 - - 0.9
150697
26 - - 73.9
151698
26 - - 58.6
68893
25 - - 0.0
54480
25
EC
- - 9.0
115460
25 - - 0.0
27411
25
EC
- - 20.6
60476
25 - - 77.8
31483
25
EC
- - 3.6
49093
25 - - 0.0
18398
24
EC
- - 41.2
121768
23 - - 52.9
103890
23
EC
- - 1.8
150832
22
EC
- - 26.1
108352
22
EC
- - 1.0
14618
22 - - 25.5
150750
21 - - 43.0
31204
21 - - 38.5
3431
20 - - 35.4
141123
20
EC
- - 1.4
151823
20
EC
- - 21.0
150772
20 - - 28.0
64990
19
EC
- - 28.2
58881
19 - - 35.7
69047
19
EC
- - 27.5
14609
19 - - 12.3
42832
19 - - 5.1
151755
18 - - 4.2
152108
18
3D
1w25A02 - 90.5
63878
18 - - 0.9
126805
18 - - 0.0
88492
18
3D
1zh2A00 - 31.2
10547
18 - - 12.5
22126
18 - - 0.9
150751
18 - - 23.1
85850
18
EC
- - 0.0
152060
18
3D
1peaA01 - 67.3
26265
17
EC
- - 48.2
78978
17 - - 10.4
68138
17 - - 0.9
122882
17 - - 9.0
150701
17 - - 47.1
25970
17
EC
- - 23.4
143865
17
EC
- - 11.0
75448
16
EC
- - 0.0
22122
16 - - 0.0
137551
16 - - 0.0
20865
16 - - 0.0
131993
16 - - 0.0
125735
16 - - 0.0
124434
16 - - 0.0
16949
16 - - 0.0
13651
LacI family
16 - - 0.0
30520
b
16 - - 0.0
131795
16 - - 0.0
141869
16
EC
- - 0.0
84743
16 - - 0.0
126793
16 - - 0.0
108799
16
EC
- - 26.5
32527
16 - - 0.0
75454
15
EC
- - 2.7
89608
15
EC
- - 0.9
152092
15
EC
- - 52.6
152285
15 - - 52.1
79213
15 - - 10.4
2454
15 - - 5.3
151776
14 - - 72.0
151616
14
EC
- - 50.6
71673
13
EC
- - 8.4
152270
13
EC
- - 83.2
151461
13
3D
1b00A00 - 37.6
151007
13
EC
- - 52.4
151575
13
EC
- - 56.9
1973
12
EC
- - 25.1
121868
12 - - 5.4
151291
12
EC
- - 53.8
151322
12 - - 57.2
151399
12
EC
- - 39.5
151687
12
3D
1i3cA00 - 42.7
151557
12
3D
3r0jA01 - 73.6
8016
12
EC
- - 17.9
151491
12
3D
4b09A01 - 2.6
55731
11 - - 19.0
151140
11
EC
- - 49.5
12836
10 - - 17.7
71976
10 - - 0.0
13720
10 - - 16.2
150735
10 - - 7.3
117342
10 - - 6.4
123174
10 - - 12.1
137470
10 - - 18.6
152180
10 - - 71.2
108354
10 - - 12.3
89375
10
EC
- - 14.4
7429
10 - - 11.6
41196
9 - - 0.0
4377
9
EC
- - 7.5
141120
9
EC
- - 0.0
151329
9 - - 0.0
42908
9 - - 0.0
12016
9 - - 0.0
151425
9
3D
4uhjA00 - 69.6
147993
9
EC
- - 0.0
27887
9 - - 8.6
152024
8 - - 59.0
60401
8 - - 19.7
151059
8 - - 26.7
151417
8 - - 2.7
151460
8
3D
1xheA00 - 37.2
2255
8 - - 0.9
42906
8
EC
- - 9.3
150322
8 - - 30.9
2403
8
EC
- - 9.3
118780
7
EC
- - 14.7
151356
7 - - 48.9
67562
7
EC
- - 18.7
134357
7
EC
- - 17.8
67536
7
3D
2gwrA01 - 29.4
150719
6 - - 20.4
5771
6 - - 29.0
75404
6 - - 8.6
144261
6 - - 18.7
33580
6 - - 9.9
41899
5
EC
- - 0.0
11689
5 - - 0.9
2189
5 - - 25.5
3682
5
EC
- - 9.2
63879
5 - - 7.8
12844
5
EC
- - 8.1
151886
5
EC
- - 24.7
152012
5
3D
3h5lA01 - 58.5
151165
5 - - 14.9
114171
5 - - 8.5
142572
5
EC
- - 0.0
150878
5 - - 13.3
86513
5 - - 3.4
151351
5 - - 45.8
136175
4
EC
- - 0.0
22756
4 - - 4.1
151855
4
3D
3eulA00 - 10.3
19609
4 - - 0.0
55803
4 - - 15.8
5492
4
EC
- - 20.8
71666
4
EC
- - 3.4
71028
4
EC
- - 14.1
32546
4 - - 14.3
4349
4
EC
- - 0.6
151141
4
3D
1w25A01 - 2.6
96743
4 - - 0.0
115462
4 - - 33.0
150921
4
3D
4if4A01 - 0.0
133161
4 - - 0.0
101029
4 - - 0.0
89398
4 - - 0.0
72047
3
EC
- - 2.5
19755
3 - - 3.2
150743
3
EC
- - 10.7
23812
3 - - 6.1
149315
3 - - 2.2
151108
3
EC
- - 33.9
150866
3 - - 25.1
150995
3
3D
2zwmA00 - 5.6
149328
3 - - 1.8
576
3 - - 8.1
135543
3 - - 8.2
150817
3 - - 0.0
144262
3
EC
- - 1.2
125484
3 - - 14.5
151194
3 - - 0.0
91051
2 - - 0.9
2203
2
EC
- - 0.0
151395
2 - - 33.8
49097
2 - - 18.2
46263
2 - - 14.0
151006
2 - - 18.5
9762
2 - - 5.9
28388
2 - - 3.2
151389
2
EC
- - 37.9
151532
2
EC
- - 29.6
55550
2 - - 11.1
51962
2
EC
- - 6.4
8206
2 - - 17.3
1305
2 - - 7.0
151948
2 - - 43.5
134359
2 - - 4.5
36995
2 - - 3.6
20858
2 - - 0.0
7426
2 - - 11.2
3247
2
EC
- - 9.2
100502
2
EC
- - 9.2
115459
2
EC
- - 6.4
7011
2 - - 17.9
27281
2
EC
- - 7.9
142734
2
EC
- - 7.5
14845
2 - - 5.3
150849
2 - - 15.8
150732
2
EC
- - 0.0
44572
2
EC
- - 10.0
140618
2 - - 0.0
151037
2
EC
- - 24.9
20863
2 - - 3.3
28647
2
EC
- - 10.7
7088
2 - - 0.0
26886
2
EC
- - 3.1
150761
1 - - 0.0
141116
1
EC
- - 0.0
150825
1
EC
- - 0.0
2406
1 - - 0.0
104708
1 - - 0.0
93027
1 - - 0.0
89397
1 - - 0.0
28731
1 - - 0.0
7564
1 - - 0.0
24281
1 - - 0.0
36992
1 - - 0.0
1215
1
EC
- - 0.0
39316
1 - - 0.0
85728
1 - - 0.0
126797
1
EC
- - 0.0
32577
1 - -
150678
1 - -
152321
1 - - 0.0
100681
1
EC
- - 0.0
29587
1 - - 0.0
130391
1 - - 0.0
27748
1 - - 0.0
126785
1 - - 0.0
4915
1 - - 0.0
44705
1
EC
- - 0.0
76210
1 - - 0.0
145028
1
EC
- - 0.0
7945
1 - - 0.0
136841
1 - - 0.0
49379
1
3D
1mvoA00 - 0.0
22121
1 - - 0.0
150788
1 - - 0.0
151024
1
EC
- - 0.0
143030
1
EC
- - 0.0
118855
1 - - 0.0
143031
1
EC
- - 0.0
150014
1 - - 0.0
151121
1 - - 0.0
130386
1
EC
- - 0.0
111869
1 - - 0.0
15695
1 - - 0.0
150867
1 - - 0.0
25478
1 - - 0.0
111969
1 - - 0.0
152199
1 - -
5102
1
EC
- - 0.0
130389
1
EC
- - 0.0
131793
1 - - 0.0
143810
1 - - 0.0
18286
1 - - 0.0
47482
1 - - 0.0
151319
1
EC
- - 0.0
10791
1
EC
- - 0.0
9114
1 - - 0.0
97119
1 - -
13374
1 - - 0.0
151647
1 - - 0.0
78980
1
EC
- - 0.0
67567
1 - - 0.0
30526
1 - - 0.0
34608
1 - - 0.0
39655
1 - - 0.0
1713
1 - - 0.0
807
1 - -