CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Rho-related GTP-binding protein RhoC

Enzyme Information

UniProtKB Entries (2)

Q6P9R4
ARHGI_MOUSE
Mus musculus
Rho guanine nucleotide exchange factor 18
P61586
RHOA_HUMAN
Homo sapiens
Transforming protein RhoA

PDB Structure

PDB 6BCB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Chen, Z., Gutowski, S., Sternweis, P.C.
Data Brief