CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase DDX19B

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q9UMR2
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q9UMR2
DD19B_HUMAN
Homo sapiens
ATP-dependent RNA helicase DDX19B

PDB Structure

PDB 6B4K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Lin, D.H., Correia, A.R., Cai, S.W., Huber, F.M., Jette, C.A., Hoelz, A.
Nat Commun