CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ras-related protein Rap-1b

Enzyme Information

UniProtKB Entries (1)

Q7LDG7
GRP2_HUMAN
Homo sapiens
RAS guanyl-releasing protein 2

PDB Structure

PDB 6AXF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Vercoulen, Y., Kondo, Y., Iwig, J.S., Janssen, A., White, K.A., Amini, M., Barber, D.L., Kuriyan, J., Roose, J.P.
Elife