CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (2)

Q9QZQ1
AFAD_MOUSE
Mus musculus
Afadin
P01112
RASH_HUMAN
Homo sapiens
GTPase HRas

PDB Structure

PDB 6AMB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Smith, M.J., Ottoni, E., Ishiyama, N., Goudreault, M., Haman, A., Meyer, C., Tucholska, M., Gasmi-Seabrook, G., Menezes, S., Laister, R.C., Minden, M.D., Marschalek, R., Gingras, A.C., Hoang, T., Ikura, M.
Nat Commun