1 keywords

CATH Domain 6agmB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Phospho-2-dehydro-3-deoxyheptonate aldolase

Enzyme Information

2.5.1.54
3-deoxy-7-phosphoheptulonate synthase.
based on mapping to UniProt P00888
Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D- arabino-hept-2-ulosonate 7-phosphate + phosphate.
-!- Formerly EC 4.1.2.15.

UniProtKB Entries (1)

P00888
AROF_ECOLI
Escherichia coli K-12
Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive

PDB Structure

PDB 6AGM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.
Cui, D., Deng, A., Bai, H., Yang, Z., Liang, Y., Liu, Z., Qiu, Q., Wang, L., Liu, S., Zhang, Y., Shi, Y., Qi, J., Wen, T.
J.Struct.Biol.