CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Pantothenate kinase |
Enzyme Information
| 2.7.1.33 |
Pantothenate kinase.
based on mapping to UniProt P9WPA7
ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.
|
UniProtKB Entries (1)
| P9WPA7 |
COAA_MYCTU
Mycobacterium tuberculosis H37Rv
Pantothenate kinase
|
PDB Structure
| PDB | 5XLV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase
Acta Crystallogr F Struct Biol Commun
|