CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

P01112
RASH_HUMAN
Homo sapiens
GTPase HRas

PDB Structure

PDB 5WPL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Exceptionally high-affinity Ras binders that remodel its effector domain.
McGee, J.H., Shim, S.Y., Lee, S.J., Swanson, P.K., Jiang, S.Y., Durney, M.A., Verdine, G.L.
J. Biol. Chem.