CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

UniProtKB Entries (1)

G7CNL4
G7CNL4_MYCT3
Mycolicibacterium thermoresistibile ATCC 19527
Inosine-5'-monophosphate dehydrogenase

PDB Structure

PDB 5K4X
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.
Park, Y., Pacitto, A., Bayliss, T., Cleghorn, L.A., Wang, Z., Hartman, T., Arora, K., Ioerger, T.R., Sacchettini, J., Rizzi, M., Donini, S., Blundell, T.L., Ascher, D.B., Rhee, K., Breda, A., Zhou, N., Dartois, V., Jonnala, S.R., Via, L.E., Mizrahi, V., Epemolu, O., Stojanovski, L., Simeons, F., Osuna-Cabello, M., Ellis, L., MacKenzie, C.J., Smith, A.R., Davis, S.H., Murugesan, D., Buchanan, K.I., Turner, P.A., Huggett, M., Zuccotto, F., Rebollo-Lopez, M.J., Lafuente-Monasterio, M.J., Sanz, O., Diaz, G.S., Lelievre, J., Ballell, L., Selenski, C., Axtman, M., Ghidelli-Disse, S., Pflaumer, H., Bosche, M., Drewes, G., Freiberg, G.M., Kurnick, M.D., Srikumaran, M., Kempf, D.J., Green, S.R., Ray, P.C., Read, K., Wyatt, P., Barry, C.E., Boshoff, H.I.
ACS Infect Dis